• Seronegative spondyloarthropathy (SSA) common features;
o Autoantibodies (RF, ANA, antiCCP, etc.) are negative.
o Enthesitis (inflammation of the area where the tendon, ligament or joint capsule attaches to the bone) plays a role in the pathogenesis.
o They mainly involve the axial skeleton. Peripheral arthritis is also seen at varying rates.
o Inflammatory low back pain is typical.
o They usually start before the age of 40.
o There is a familial predisposition, they are associated with varying degrees of HLA-B27 positivity.
o Oculo-mucocutaneous findings may accompany.
• SPA group diseases;
o Ankylosing spondylitis (AS)
o Psoriatic arthritis (PsA)
o Reactive arthritis (ReA)
o Enteropathic arthritis (EpA)
Characteristics of inflammatory low back pain
Begins under the age of 40
Insidious onset, lasting longer than 3 months
There is morning stiffness (> 30 minutes)
relieved by exercise, worsened by rest.