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ROSEOLA INFANTUM (6. DISEASE) (ECZANTEM SUBITU)

• Roseola infantum is a rash disease caused by Human Herpesvirus type 6 (HHV6) in the majority of cases and Human Herpesvirus type 7 (HHV7) in a small number of cases.

• The importance of roseola infantum is that it mimics other serious diseases characterized by high fever and can cause febrile convulsions.

Clinic

• Roseola infantum is usually seen in children aged 6 months to 4 years and 90% before 2 years of age.

• The most important clinical finding of the disease is sudden onset fever, which can reach 40.6°C and lasts in 2-8 days (average 4 days). The patient is generally well except for high fever.

• The fever subsides rapidly and a characteristic rash appears after the fever subsides.

• The rash typically starts on the trunk and spreads to the face, neck and extremities. "Rose-pink" macules or maculopapules 2-3 mm in diameter usually coalesce and heal within 1-2 days without leaving any pigmentation or desquamation.

Complications

• Febrile convulsion (most common)

• Meningoencephalitis or aseptic meningitis (in some cases HH6 directly infects the CNS).

• Multiorgan disease (pneumonia, hepatitis) may develop in immunocompromised patients.

• Encephalitis and pseudotumor cerebri may develop.

• PALE (posttransplant acute limbic encephalopathy): Memory problems, insomnia, confusion and convulsions are seen after bone marrow transplantations.


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Illness that is not contagious when the rash appears ... Erythema infectiosum

ROSEOLA-INFANTUM


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