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Fat Embolism Syndrome

General Information

• The presence of fat embolism in the circulation after long bone fractures or major trauma is called fat embolism, and its clinical manifestations are called fat embolism syndrome. It can occur in three clinical forms:

1- Subclinical

Only the Pa02 value is below 60 mmHg.

2- Clinic

It is the typical form and occurs 24-72 hours after trauma.

Major findings

 Respiratory failure (Pa02<60, PC02>55 mmHg)

 Cerebral involvement

 Petechial hemorrhages

 Retinal findings

Minor findings

Fever (39-40 °C)

 Tachycardia

 Liver failure

oliguria, anuria

 Anemia, thrombocytopenia, leukocytosis

ECG findings


Diagnosis

Fat globulins + 1 major + 4 minor findings.


3- Fulminant

It occurs hours after the trauma, its clinic is very painful.

The most important criterion in fat embolism syndrome is that PaO/ is below 60 mmHg.

Treatment is supportive therapy. Given adequate treatment, it is usually self-limiting and resolves in 1-2 weeks.

The most important measure to prevent its occurrence is to immobilize the fracture as soon as possible. 

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