|
Hematology |
|
|
Disease |
Possible Treatment |
|
Hydrops-related anemia (erythroblastosis fetalis) |
Umbilical vein erythrocyte transfusion |
|
thalassemia |
Fetal stem cell transplantation |
|
Thrombocytopenia (isoimmune) |
Umbilical vein platelet transfusion, intravenous immunoglobulin to the
mother |
|
ITP |
Steroids and intravenous immunoglobulin to the mother |
|
chronic granulomatous disease |
Fetal stem cell transplantation |
|
Metabolic - Endocrine |
|
|
Disease |
Possible Treatment |
|
Phenylketonuria in the mother |
Restriction of phenylalanine |
|
Fetal galactosemia |
galactose free diet |
|
21-Hydroxylase deficiency |
dexamethasone |
|
Multiple carboxylase deficiency |
If it responds, biotin |
|
Methylmalonic acidemia |
Vitamin B12 if responsive |
|
Maternal Diabetes |
Pregnancy, labor, tight blood sugar control during pregnancy |
|
fetal goiter |
Maternal hyperthyroidism-maternal propylthiouracil, fetal
hypothyroidism-intraamniotic T4 |
|
Fetal Stress |
|
|
Disease |
Possible Treatment |
|
hypoxia |
Oxygen to mother, position |
|
Intrauterine growth retardation |
Oxygen, position, nutritional support if insufficient |
|
Oligohydramnios, variable degree of premature rupture of membranes |
Amnioinfusion (antepartum and intrapartum) |
|
polyhydramnios |
Reducing the amnion (consecutive), if necessary
indomethacin (reduces fetal urine output) |
|
Supraventricular tachycardia |
Digoxin, flecainide, procainamide, amiodarone, quinidine to the mother |
|
Lupus anticoagulant |
Maternal aspirin, prednisone |
|
Amniotic fluid dyed with meconium |
amnioinfusion |
|
Early birth |
Sympathomimetics, magnesium sulfate, antibiotics |
|
congenital heart block |
Dexamethasone, pacemaker |
|
Respiratory |
|
|
Disease |
Possible Treatment |
|
Pulmonary immaturity |
Dexamethasone, betamethasone |
|
Bilateral chylotarax pleural effusions |
Thoracentesis, Pleuroamniotic shunt |
|
Congenital Anomalies |
|
|
Disease |
Possible Treatment |
|
neural tube defect |
Folate, vitamins (preservative) |
|
Diaphragmatic hernia |
Surgery (correction or treatment of tracheal plug) |
|
Obstructive uropathy (oligohydramnios without renal dysplasia) |
Vesicoamniotic shunt + amniofusion, posterior urethral
valve ablation |
|
Cystic adenomatoid malformation (with hydrops) |
Pleuroamniotic shunt or resection |
|
Infectious Disease |
|
|
Disease |
Possible Treatment |
|
group B streptococcus |
Ampicillin, penicillin |
|
Chorioamnionitis |
antibiotics |
|
Toxoplasmosis |
Spiramycin, pyrimycin, sulfadiazine and folic acid |
|
syphilis |
Penicillin |
|
Tuberculosis |
Antituberculosis drugs |
|
Lyme disease |
penicillin, ceftriaxone |
|
parvovirus |
Intrauterine erythrocyte transfusion for hydrops and severe anemia |
|
Chlamydia trachomatis |
erythromycin |
|
HIV-AIDS |
AZT or abacavir + lamivudine or emtricitabine + protease inhibitors or
integrase inhibitors or non-nucleoside analogues |
|
cytomegalovirus |
Ganciclovir from the umbilical vein |
|
Other |
|
|
Disease |
Possible Treatment |
|
Non-immune hydrops (anemia) |
Red blood cell transfusion from the umbilical vein |
|
Narcotic withdrawal (discontinuation) |
Low-dose metadan to the mother |
|
severe combined immunodeficiency disease |
Fetal stem cell transplantation |
|
sacrococcygeal teratoma |
In utero resection or vessel obliteration |
|
twin-twin transfusion syndrome |
Repeated amniocentesis, photocoagulation of common vessels with
YAG-laser |
|
Twin reverse arterial perfusion syndrome (TRAP) |
Digoxin, indomethacin, cord occlusion |
|
Multiple fetus pregnancy |
Reducing the number of choosing |
|
hemochromatosis |
Giving IVIG to the mother |