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Salivery Gland Tumors


Salivary Glands

 Major Salivary Glands:
 Parotid-Submandibular gland-Sublingual gland
Minor Salivary Glands:
It is distributed in approximately 1000 numbers in the oropharyngeal mucosa.
Unlike the parotid submandibular gland, it contains lymphoid tissue.
The submandibular gland makes most of the 1500 cc saliva secretion per day.
parotid; produces pure serous secretion.
Sialolithiasis:
It occurs most frequently (80%) in the submandibular gland.
Ranula:
A mucus retention cyst of the sublingual gland is called
Case
Patient with swelling in the submandibular region during meals
If swelling resolves after eating, sialolithiasis should be considered.

Salivary Gland Tumors

80% occur in the parotid
20% of parotid tumors are malignant. 65% of minor and sublingual glands are malignant

Benign Tumors

Pleomorphic adenoma

Known as a benign mixed tumor
Pleomorphic adenoma most commonly develops in the parotid gland.
Histologically, there are pseudopods in the tumor.
most common salivary gland tumor

Whartin's tumor

Papillary cystadenoma lymphomatosum
It is the most common tumor after pleomorphic adenoma.
It is 4 times more common in men. Associated with smoking
It is the most common bilateral salivary gland tumor.
Most common in parotid

oncocytoma

 It is a salivary gland tumor rich in mitochondria and seen in advanced age.

hemangioma

Malignant Tumors

mucoepidermoid carcinoma

 It is the most common malignant tumor and most commonly localized in the parotid.

adenoid cystic carcinoma

Submandibular and minor is the most common malignant tumor of the salivary glands.
It is called a "cylindricaloma" because of the cylindrical cells
Perineural invasion occurs in SO% of patients
Perineural invasion recurs frequently after surgery
Salivary gland tumor propagating through nerves

Malignant mixed tumor

Bening pleomorphic adenoma + malignant tumor tissue coexist
It develops from the background of pleomorphic adenoma that has not been operated for many years (after 10 years).
Other name: Carsinoma ex pleomorphic adenoma

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